The primary objective of this study was to evaluate the effectiveness of parenting skills training on perceived stress and addiction tendency among adolescents in Tabriz city. The statistical population comprised all parents of female secondary school students (second stage) in District 3 of Tabriz, totaling 15,452 individuals. The sample included 30 parents of at-risk female secondary school students from the same district, divided equally into an experimental group (15 parents) and a control group (15 parents), selected through purposive sampling. Data were collected using the Perceived Stress Scale developed by Cohen et al. (1986), the Addiction Readiness Questionnaire by Weed and Butcher (1992), and a parenting skills training program. The data were analyzed using analysis of covariance (ANCOVA). The results demonstrated that parenting skills training significantly reduced perceived stress among adolescents in Tabriz. Additionally, the training had a significant impact on decreasing adolescents’ tendency toward addiction (p < 0.05).